Honeycombs are essential elements in mechanical systems where low weight and high strength are required. Aluminum and Nomex® are the most commonly used honeycomb materials in structures exposed to compression stress. The primary purpose of this study is to verify the compression behavior of honeycombs in Ls-Dyna using experimental values and theoretical equations. Additionally, it is aimed to evaluate the honeycombs parameters such as cell diameter, cell wall thickness, and material. A correlation matrix was created using the Python/Seaborn program to examine the impact coefficients of the parameters. In this way, the effect of design parameters on compression strength and internal energy was investigated.