A study of the effects of male smoking and alcohol consumption on the outcomes of the In Vitro Fertilization treatments involving young, fertile oocyte donors in Northern Cyprus. Data from 124 consecutive IVF cycles were analyzed retrospectively. Patient files and clinical records were used to collect information on male smoking and alcohol habits, semen analysis parameters, and IVF outcomes. SPSS software was one of the statistical techniques used to compare the results of several groups according to their alcohol and smoking habits. Statistical significance was set at a p-value of less than 0.05. The normal concentration of sperms, the morphology and motility rate were considerably less in the smokers and drinkers group than in the nonsmokers and non-drinkers group, by 14%, 8.1% and 15.2%, correspondingly. Fur-thermore, for males over 40, the drinking and smoking group has a considerably reduced pro-portion of normal sperm volume by 7% compared to the equivalent group for males under 40. This research shows that the act of smoking and the consumption of alcohol by males lessen the quality of sperm and have a negative influence on the outcomes of in vitro fertilization. The percentage of positive beta-human chorionic gonadotropin was about 21% lower in males who smoke and drink than those who abstain. These findings highlight the significance of providing counseling to males undergoing IVF regarding the potential adverse effects of these lifestyle habits on their fertility potential.